Patient Education
Menopause & Perimenopause
What actually happens, how perimenopause differs from menopause, and what the treatment options really are — hormonal and otherwise.
Menopause is a single point in time: twelve consecutive months without a period. Everything leading up to it is perimenopause, and that transition can run for several years, with fluctuating hormones producing symptoms long before periods actually stop. A great deal of the confusion around menopause comes from conflating the two.
Not everyone has significant symptoms, and there is no single right answer for those who do. The decision about hormone therapy in particular has been shaped by headlines that oversimplified the research, and it deserves a real conversation rather than a reflex.
Symptoms and warning signs
- Hot flashes and night sweats
- Irregular periods — closer together, further apart, heavier, or lighter
- Sleep disturbance, often independent of night sweats
- Vaginal dryness, and discomfort or pain with intercourse
- Mood changes, irritability, anxiety, or low mood
- Difficulty with concentration and memory
- Reduced libido
- Urinary urgency and more frequent urinary infections
- Joint aches and stiffness
- Changes in skin, hair, and body composition
Factors that influence timing and severity
- Age — menopause most often occurs in the late forties to early fifties
- Family history, which is a reasonable predictor of your own timing
- Smoking, which is associated with an earlier menopause
- Surgical removal of the ovaries, which causes immediate menopause
- Chemotherapy or pelvic radiation
- Certain autoimmune conditions
- Primary ovarian insufficiency, where the ovaries stop functioning before 40
How it is diagnosed
- The clinical picture — pattern of periods and symptoms — which is usually sufficient on its own
- FSH and estradiol blood levels, useful mainly in younger women or where the picture is unclear
- Thyroid function testing, since thyroid disease can mimic many of the same symptoms
- Pelvic examination, to assess vaginal and urogenital changes
- Bone density scanning, as bone loss accelerates after menopause
- Pregnancy testing where periods have become irregular and conception is still possible
Treatment options
Options fall into hormonal and non-hormonal, and the right choice depends on your symptoms, your medical history, and your own view of the trade-offs.
- Systemic hormone therapy — estrogen, with progesterone if you have a uterus
- Local vaginal estrogen, which treats dryness and urinary symptoms with minimal systemic absorption
- Non-hormonal prescription medications for hot flashes, including certain antidepressants and newer targeted agents
- Vaginal moisturizers and lubricants
- Cognitive behavioral therapy and treatment of sleep disturbance
- Calcium, vitamin D, and weight-bearing exercise for bone protection
- Bone-protective medication where bone density is already reduced
- Addressing cardiovascular risk factors, which change after menopause
Dr. V on menopause and perimenopause
Her videos on treating hot flashes and on vaginal dryness cover the two most common symptoms in more detail.
When to book an appointment
- Symptoms are affecting your sleep, your work, or your relationships.
- You want to understand hormone therapy properly before deciding either way.
- Your periods have changed and you are not sure whether this is perimenopause.
- You have any bleeding after menopause — this always needs evaluating.
Frequently Asked Questions
1What exactly is menopause, and does everyone get symptoms?
2What is perimenopause, and how is it different?
3What options are there for treatment? Are they all hormonal?
4What are the risks of taking hormones? Are there any risks if I don't?
5I am bleeding again after menopause. Is that normal?
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Take control of your health.
Menopause deserves a proper conversation rather than a headline. Book an appointment — or join Dr. Varkey's free seminar on menopause and perimenopause.
Request an Appointment